| # | Div | Day | Date | KO | Field | Home | Away | Home | Away |
|---|---|---|---|---|---|---|---|---|---|
| 4501 | 1516X | Wed | May 21 | 8:45pm | N. London Stadium | Whitecaps 16G | Ilderton 15G | Whitecaps | Ilderton |
| 4502 | 1516X | Sun | May 25 | 11:00am | Tom Tipton Park | Soo City United 15G | Sarnia 16G | Soo City | Sarnia |
| 4503 | 1516X | Tue | May 27 | 8:30pm | Windermere 3 | Alliance 15G | Guelph 16G | Alliance | Guelph |
| 4504 | 1516X | Wed | May 28 | 8:00pm | Western Alumni Field | Ilderton 15G | BVB Waterloo 16G | Ilderton | Waterloo |
| 4505 | 1516X | Tue | Jun 3 | 7:00pm | University of Guelph West U13+ | Guelph 15G | London Dinamo 16G | Guelph | Ldn Dinamo |
| 4506 | 1516X | Tue | Jun 10 | 8:00pm | Western Alumni Field | Ilderton 15G | Guelph 16G | Ilderton | Guelph |
| 4507 | 1516X | Wed | Jun 11 | 7:00pm | Veterans Field X | Sarnia 16G | Ilderton 15G | Sarnia | Ilderton |
| 4508 | 1516X | Sat | Jun 14 | 3:00pm | Tom Tipton Park | Soo City United 16G | Alliance 15G | Soo City | Alliance |
| 4509 | 1516X | Wed | Jun 18 | 9:00pm | TBD #4 | BVB Waterloo 16G | Alliance 15G | Waterloo | Alliance |
| 4510 | 1516X | Sat | Jun 21 | 2:00pm | Tom Tipton Park | Soo City United 15G | London Dinamo 16G | Soo City | Ldn Dinamo |
| 4511 | 1516X | Sun | Jun 22 | 11:00am | Tom Tipton Park | Soo City United 15G | BVB Waterloo 16G | Soo City | Waterloo |
| 4512 | 1516X | Wed | Jul 2 | 8:30pm | Windermere 2 | London Dinamo 16G | Alliance 15G | Ldn Dinamo | Alliance |
| 4513 | 1516X | Tue | Jul 8 | 7:00pm | University of Guelph West U13+ | Guelph 15G | Whitecaps 16G | Guelph | Whitecaps |
| 4514 | 1516X | Sat | Jul 19 | 1:00pm | Citywide Field #2 | Ilderton 15G | Caboto 16G | Ilderton | Caboto |
| 4515 | 1516X | Sat | Jul 19 | 2:00pm | Tom Tipton Park | Soo City United 16G | Guelph 15G | Soo City | Guelph |
| 4516 | 1516X | Sat | Jul 19 | 4:00pm | Tom Tipton Park | Soo City United 15G | Guelph 16G | Soo City | Guelph |
| 4517 | 1516X | Sun | Jul 20 | 11:00am | Windermere 2 | Alliance 15G | Caboto 16G | Alliance | Caboto |
| 4518 | 1516X | Wed | Jul 23 | 7:00pm | Veterans Field X | Sarnia 16G | Alliance 15G | Sarnia | Alliance |
| 4519 | 1516X | Wed | Jul 30 | 7:00pm | RIM Park AF1 | BVB Waterloo 16G | Guelph 15G | Waterloo | Guelph |
| 4520 | 1516X | Thu | Jul 31 | 8:30pm | Citywide Field #2 | London Dinamo 16G | Ilderton 15G | Ldn Dinamo | Ilderton |
| 4521 | 1516X | Sat | Aug 9 | 2:00pm | Bishop Macdonell HS | Guelph 15G | Sarnia 16G | Guelph | Sarnia |
| 4522 | 1516X | Sun | Aug 10 | 9:00am | Tom Tipton Park | Soo City United 15G | Caboto 16G | Soo City | Caboto |
| 4523 | 1516X | Tue | Aug 12 | 8:30pm | Windermere 3 | Alliance 15G | Whitecaps 16G | Alliance | Whitecaps |
| 4524 | 1516X | Sun | Aug 24 | 11:00am | Tom Tipton Park | Soo City United 16G | Ilderton 15G | Soo City | Ilderton |
| 4525 | 1516X | Sat | Aug 30 | 1:00pm | Holy Names High School Turf | Caboto 16G | Guelph 15G | Caboto | Guelph |
| 4526 | 1516X | Sun | Aug 31 | 11:00am | Tom Tipton Park | Soo City United 15G | Whitecaps 16G | Soo City | Whitecaps |
Games to be Rescheduled
| # | Div | Day | Date | KO | Field | Home | Away | Home | Away |
|---|
